Although the human toxicology of lead has probably been more extensively studied that that of any other toxic element, until the last few years attention has been focused on (1) the effects of industrial exposure of adult males at levels sufficient to produce obvious clinical symptoms and signs, and (2) the effects of clinical lead poisoning in children, generally from chewing painted objects. The convenient concept of supposedly safe threshold levels has been increasingly challenged in recent years. Evidence for children suggests that a continuum of "sub-clinical" toxic effects on brain function extend down to body lead levels previously regarded as normal. Thi s review is largely concerned with adverse effects on behaviour and intelligence in normally asymptomatic children which appear to be associated with disturbances of brain maturation and function resulting from pre and post-natal exposure to lead at "normal" environmental levels. The relative importance of dietary and airborne lead is discussed in this context. /TRRL/

  • Corporate Authors:

    Royal Swedish Academy of Science

    Universitetsforlaget, P.O. Box 307, Blindern
    Oslo 3,   Norway 
  • Authors:
    • Bryce-smith, D
    • Mathews, J
    • Stephens, R
  • Publication Date: 1978

Media Info

  • Features: Figures; Photos; References; Tables;
  • Pagination: p. 192-203
  • Serial:
    • Ambio
    • Volume: 7
    • Issue Number: 5/6
    • Publisher: Royal Swedish Academy of Sciences

Subject/Index Terms

Filing Info

  • Accession Number: 00195506
  • Record Type: Publication
  • Source Agency: Swedish National Road and Transport Research Institute (VTI)
  • Files: ITRD, TRIS
  • Created Date: Sep 15 1979 12:00AM