Adaptive and Maladaptive Impulsivity, Platelet Monoamine Oxidase (MAO) Activity and Risk-admitting in Different Types of Risky Drivers

Platelet monoamine oxidase (MAO) activity reflects serotonergic functioning associated with impulsive behavior, but the significance of these associations to real-life impulsive behavior in healthy subjects is not clear. This paper explores impulsivity and platelet MAO activity among people with driving violations. The authors compare facets of impulsivity and platelet MAO activity in 1,004 male drivers, of whom 203 had been caught by the police driving drunk and 292 had been caught exceeding speed limits and committing other non-alcohol-related driving violations. Subjects with speeding and other non-alcohol-related violations were further divided according to their self-reported risk-admitting of exceeding speed limits. While drunk driving was associated only with maladaptive types of impulsivity, exceeding speed limits was associated with functional impulsivity and excitement seeking and, to a lesser degree, with dysfunctional impulsivity. Drunk drivers had lower platelet MAO activity. Risk-admitting high-risk drivers had higher platelet MAO activity, neuroticism-related impulsivity, dysfunctional impulsivity, and excitement seeking compared to all other groups and higher functional impulsivity compared to controls. Risk-denying high-risk drivers had only higher functional impulsivity compared to controls. This study indicates different expressions of functional and dysfunctional impulsivity in behavior. While platelet MAO activity is lower in alcohol-related risky behavior, non-alcohol-related self-acknowledged risky behavior is related to higher platelet MAO activity. Thus, deviance towards lower as well as higher end of central serotonergic functioning may lead to impulsive behavior. While self-reported impulsivity did not correlate with MAO activity, both MAO activity and impulsivity were related to risky behavior.

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  • Authors:
    • Paaver, Marika
    • Eensoo, Diva
    • Pulver, Aleksander
    • Harro, Jaanus
  • Publication Date: 2006

Language

  • English

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Filing Info

  • Accession Number: 01076351
  • Record Type: Publication
  • Files: TRIS
  • Created Date: Sep 3 2007 8:44PM