IN VIVO CERVICAL FACET CAPSULE DISTRACTION: MECHANICAL IMPLICATIONS FOR WHIPLASH AND NECK PAIN

The purpose of this research was to investigate the relationship between capsular ligament strain, facet joint distraction, cellular nociceptive responses, and pain. Though there is much research pointing to mechanical injury of the cervical facet joint as a mechanism of whiplash injury, it is uncertain that it has the potential to cause pain. A rat model of in vivo facet joint injury was utilized to impose C6/C7 joint distraction in separate studies of subcatastrophic and physiologic vertebral distraction, as well as sham procedures. In order to quantify resulting pain symptoms, a common clinical measure of behavioral hypersensitivity (allodyna) was measured for 14 days after injury. In addition, spinal activation of microglia and astrocytes was quantified, on day 14, to examine the potential role of glial activation as a physiologic mechanism of facet-mediated painful injury. Results of the study suggest that facet capsule strains comparable to those previously reported for subcatastrophic failures of this ligament and whiplash kinematics have the potential to produce pain symptoms and alter one element of nociception. In addition, results also suggest that a mechanical threshold likely exists for painful joint distraction, providing physiologic and behavioral evidence of the cervical facet joint's mechanical injury as a source of neck pain.

Language

  • English

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Filing Info

  • Accession Number: 00988826
  • Record Type: Publication
  • ISBN: 0768014468
  • Report/Paper Numbers: 2004-22-0016
  • Files: TRIS
  • Created Date: Apr 13 2005 12:00AM