SIDE EFFECTS AND SKILLS RELATED TO DRIVING AFTER INTRAMUSCULAR ADMINISTRATION OF BUPSIVACAINE AND ETIDOCAINE

Eleven healthy subjects were injected intramuscularly with a saline placebo, 1.3 mg/kg of 0.5% plain bupivacaine, or 2.6 mg/kg of 1.0% plain etidocaine in a double-blind cross-over fashion. Before and at 1/2, 2 and 4 hours after injection, side effects were recorded, and psychomotor skills related to driving were measured. Fatigue, dizziness, and sore thighs were significantly more common with etidocaine than with bupivacaine or the saline solution. Bupivacaine significantly impaired eye-hand coordination and flicker fusion discrimination during the whole observation period. Etidocaine impaired flicker fusion discrimination only. The subjects' adaption to darkness, sensitivity to brightness, and visual discrimination ability in bright counterlight remained unaltered after each treatment. The results suggest that such psychomotor performance as driving ability is impaired for at least 2 hours after a patient receives 1.3 mg/kg of plain bupivacaine or 2.6 mg/kg of plain etidocaine intramuscularly. /Author/

• Authors:
  • Korttila, K
  • Hakkinen, S
  • LINNOILA, M
• Publication Date: 1975

Media Info

• Features: Figures; References; Tables;
• Pagination: p. 384-391
• Serial:
  • Acta Anaesthesiologica Scandinavica
  • Volume: 19

Subject/Index Terms

• TRT Terms: Driver performance; Drivers; Drugs; Motor skills; Personnel performance; Placebos; Seawater; Visual perception
• Uncontrolled Terms: Psychomotor performance
• Subject Areas: Highways; Safety and Human Factors;

Filing Info

• Accession Number: 00148790
• Record Type: Publication
• Source Agency: National Safety Council Safety Research Info Serv
• Files: TRIS
• Created Date: Mar 30 1977 12:00AM