MEDICINES AND DRIVER FITNESS: FINDINGS FROM A METAANALYSIS OF EXPERIMENTAL STUDIES AS BASIC INFORMATION TO PATIENTS, PHYSICIANS AND EXPERTS

Holding an enquiry into the topic 'medicines and driver fitness' sponsored by the Federal Highway Research Institute more than 1000 published experimental studies on performance following drug intake were gathered. By means of a meta-analytic approach important information of the studies were PC-extracted (among other things: number, age and sex of subjects, manner of treatment, time between drug intake and testing, tasks presented and the experimental findings) and analysed with the help of inferential statistics. Three examples will prove the benefit of this methodological approach: applied to diazepam detailed statements on kind, intensity and duration of impairment are given. A comparison between the alterations of some benzodiazepines assist the physicians in prescribing an optimum substance to drivers. The combination of blood concentration curves and time dependent curve of impairment can be a valuable tool to experts judging the danger of a medicine in terms of substance concentration. (a) For the record of the covering entry of this conference, please see IRRD abstract no 868581.

• Record URL:
  http://www.icadtsinternational.com/documents/?category=13th_T1995_Adelaide
• Availability:
  • Find a library where document is available. Order URL: http://worldcat.org/isbn/0908204213
• Corporate Authors:

  NH&MRC ROAD ACCIDENT RESEARCH UNIT

  UNIVERSITY OF ADELAIDE
  ADELAIDE, SOUTH AUSTRALIA  Australia  5005
• Authors:
  • Berghaus, G
  • GUO, B-L
• Conference:
  • ALCOHOL, DRUGS AND TRAFFIC SAFETY - T'95, 13 AUGUST - 18 AUGUST 1995; PROCEEDINGS OF THE 13TH INTERNATIONAL CONFERENCE ON ALCOHOL, DRUGS AND TRAFFIC SAFETY, ADELAIDE
• Publication Date: 1995

Language

• English

Media Info

• Features: References;
• Pagination: p. 295-300
• Serial:
  • Volume: 1

Subject/Index Terms

• TRT Terms: Conferences; Diseases and medical conditions; Driver performance; Drivers; Drugs; Performance; Travelers
• ITRD Terms: 8525: Conference; 1772: Driver; 2242: Drugs; 2154: Medical aspects; 2205: Skill (road user)
• Subject Areas: Safety and Human Factors; Society;

Filing Info

• Accession Number: 00731270
• Record Type: Publication
• Source Agency: ARRB
• ISBN: 0-908204-21-3
• Files: ITRD, ATRI
• Created Date: Feb 27 1997 12:00AM