ETHANOL IMPAIRS SPATIAL COGNITIVE PROCESSING: NEW BEHAVIORAL AND ELECTROPHYSIOLOGICAL FINDINGS

This article presents behavioral and electrophysiological evidence that one of ethanol's major effects in the brain is a marked impairment in spatial cognitive processing. The behavioral evidence indicates that ethanol produces deficits on tasks requiring spatial memory and spatial learning. The electrophysiological evidence indicates that ethanol degrades the spatial specificity of hippocampal place cells. Togther, these results suggest a neurophysiological basis for an animal's impaired performance on spatial navigation tasks while intoxicated. Such impaired performance in spatial cognitive processing could well be a factor in impaired performance by intoxicated humans on tasks requiring spatial navigation, such as automobile driving.

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  • Corporate Authors:

    Cambridge University Press

    32 Avenue of the Americas
    New York, NY  United States  10013-2473
  • Authors:
    • Matthews, D B
    • Best, P J
    • White, A M
    • Vandergriff, J L
    • Simson, P E
  • Publication Date: 1996-8

Language

  • English

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Filing Info

  • Accession Number: 00726799
  • Record Type: Publication
  • Files: TRIS
  • Created Date: Oct 3 1996 12:00AM