GAS CHROMATOGRAPHIC ANALYSIS OF INHALATION ANESTHETICS IN WHOLE BLOOD BY AN EQUILIBRATION METHOD

A gas chromatographic procedure for the quantitative analysis of the inhalation anesthetics in blood was devised. A blood sample was equilibrated in 10 ml. or 20 ml. glass vial. After equilibration 1 ml. of the gas in the vial was introduced into a gas chromatograph and the anesthetic concentration in blood was measured from that in gas phase by means of a calibration curve prepared from appropriate standards. A thermal conductivity detector was used for the analysis of nitrous oxide, cyclopropane and ether, while a flame ionization detector was used for halothane, methoxyflurane and low concentration of ether. Concentrations in blood of inhalation anesthetics now available can be measured accurately by this method.

  • Availability:
  • Corporate Authors:

    Lippincott (JB) Company

    East Washington Square
    Philadelphia, PA  United States  19105
  • Authors:
    • Yamanura, H
    • Wakasugi, B
    • Sato, S
    • Takebe, Y
  • Publication Date: 1966-5

Media Info

  • Features: Figures; References; Tables;
  • Pagination: p. 311-317
  • Serial:
    • Anesthesiology
    • Volume: 27
    • Issue Number: 3
    • Publisher: Lippincott (JB) Company
    • ISSN: 0003-3022

Subject/Index Terms

Filing Info

  • Accession Number: 00495324
  • Record Type: Publication
  • Source Agency: National Highway Traffic Safety Administration
  • Report/Paper Numbers: HS-039 620
  • Files: HSL, USDOT
  • Created Date: Jul 31 1990 12:00AM