A group of twenty depressive patients was compared during a 3-4 month course of antidepressant therapy (maprotiline: N = 6, age = 46.1; dibenzepin: n = 4, age = 43.0; lithium: N = 6, age = 44.5; "mixed: (maprotiline, dibenzepin trimeprimine): n = 4, age = 50.2) with a healthy control group (n = 32, age = 38.2) for subjective assessment of their depressive mood and performance as well as objective measurement of variables relating to driving behaviour. The measurements were taken 2-4 weeks after a pre-treatment period (day 1) and after 2-3 months of further therapy (day 2). During therapy, all patients felt "less depressive": and "more capable" in subjective terms. All patient groups made learning progress in the objectively measured variables (psychomotor coordination and attentiveness tests). By day 2, the patient groups had almost reached the performance level of the control group, providing they received antidepressant therapy (regardless of the action profile) which was suitable for the basic disorder and the symptons, and therapy was successful in the opinion of the physician. It may be concluded that depressive patients, assuming suitable antidepressant treatment and good response, are capable of driving while under maintenance theraphy. (Author/TRRL)

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    Cambridge Medical Publication Limited

    435-437 Wellingborough Road
    Northampton NN1 4EZ,   England 
  • Authors:
    • HOBI, V
    • Gastpar, M
    • Gastpar, G
    • Gilsdorf, U
    • Kielholz, P
    • Schwarz, E
  • Publication Date: 1982

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Filing Info

  • Accession Number: 00396638
  • Record Type: Publication
  • Source Agency: Transport Research Laboratory
  • Files: ITRD, TRIS
  • Created Date: Sep 30 1985 12:00AM