HERBICIDE EXPOSURE AND TUMOR MORTALITY. AN UPDATED EPIDEMIOLOGIC INVESTIGATION ON SWEDISH RAILROAD WORKERS

A group of 348 individuals has been followed through October 1978. In this updated analysis of the causes of death among railroad workers, the observed number of tumor deaths was higher than expected especially among individuals exposed in earlier years of the study to both amitrol and phenoxy acids. However, the excess tumor mortality among persons exposed to amitrol became more moderate, and the earlier, slightly increased tumor mortality among people exposed to phenoxy acids more pronounced. No specific type of tumor predominated. The result of the previous analysis of deaths among these railroad workers has been confirmed as to an excess of tumors, but the aspects of casual relationships to specific agent remain rather unclear, especially since workers exposed to a combination of amitrol and phenoxy acids seem to be the most seriously affected. However, the result being in agreement with animal data and other epidemiologic studies, suggests a need for the careful handling of amitrol and phenoxy acids as increasingly suspicious carcinogens.

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  • Corporate Authors:

    Institute of Occupational Health

    Haartmaninkatu 1
    SF-00290 Helsinki 29,   Finland 
  • Authors:
    • Axelson, O
    • Sundell, L
  • Publication Date: 1980

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Filing Info

  • Accession Number: 00330197
  • Record Type: Publication
  • Source Agency: International Union of Railways
  • Files: TRIS
  • Created Date: Jun 12 1981 12:00AM