Driving Performance of Depressed Patients Who Are Untreated or Receive Long-Term Antidepressant (SSRI/SNRI) Treatment

This article reports on a study undertaken to assess the actual driving performance of patients with depression who were classified into three groups: patients receiving either no antidepressant treatment (with or without benzodiazepine medication) or treatment with selective serotonin/noradrenalin reuptake inhibitors for a period of 6-52 weeks. The study featured a standardized on-the-road driving test to assess standard deviation of lateral position (SDLP) in the 3 patient groups. Severity of depression was assessed using Beck's Depression Inventory and the Hamilton Depression Rating Scale. The performance of patient groups was also compared to healthy controls. The authors found that the mean SDLP of untreated and treated patients was significantly higher than that of healthy controls. However, driving impairment in the long-term treated group was significantly less than in the untreated groups. SDLP was positively correlated to severity of depression across all groups. The authors conclude with a discussion of their findings of the correlation between depressive symptoms and driving impairment, noting that reductions in severity of depression by using antidepressants also reduces the severity of driving impairment.


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  • Accession Number: 01677836
  • Record Type: Publication
  • Files: TRIS
  • Created Date: Mar 8 2018 4:19PM