Associations of Night-Time Road Traffic Noise with Carotid Intima-Media Thickness and Blood Pressure: The Whitehall II and SABRE Study Cohorts.

Road traffic noise has been linked to increased risk of stroke, for which hypertension and carotid intima-media thickness (cIMT) are risk factors. A link between traffic noise and hypertension has been established, but there are few studies on blood pressure and no studies on cIMT. To examine cross-sectional associations for long-term exposure to night-time noise with cIMT, systolic blood pressure (SBP), diastolic blood pressure (DBP) and hypertension. The study population consisted of 2592 adults from the Whitehall II and SABRE cohort studies living within Greater London who had cIMT, SBP and DBP measured. Exposure to night-time road traffic noise (A-weighted dB, referred to as dBA) was estimated at each participant's residential postcode centroid. Mean night-time road noise levels were 52dBA (SD=4). In the pooled analysis adjusted for cohort, sex, age, ethnicity, marital status, smoking, area-level deprivation and NOx there was a 9.1mum (95% CI: -7.1, 25.2) increase in cIMT in association with 10dBA increase in night-time noise. Analyses by noise categories of 55-60dBA (16.2mum, 95% CI: -8.7, 41.2), and >60dBA (21.2mum, 95% CI: -2.5, 44.9) vs. <55dBA were also positive but non-significant, expect among those not using antihypertensive medication and exposed to >60dBA vs. <55dBA (32.6mum, 95% CI: 6.2, 59.0). Associations for SBP, DPB and hypertension were close to null. After adjustments, including for air pollution, the association between night-time road traffic noise and cIMT was only observed among non-medication users but associations with blood pressure and hypertension were largely null.

  • Record URL:
  • Availability:
  • Supplemental Notes:
    • Copyright © 2016 Elsevier Ltd. All rights reserved.
  • Authors:
    • Halonen, Jaana I
    • Dehbi, Hakim-Moulay
    • Hansell, Anna L
    • Gulliver, John
    • Fecht, Daniela
    • Blangiardo, Marta
    • Kelly, Frank J
    • Chaturvedi, Nish
    • Kivimaki, Mika
    • Tonne, Cathryn
  • Publication Date: 2017-1


  • English

Media Info

Subject/Index Terms

Filing Info

  • Accession Number: 01729627
  • Record Type: Publication
  • Files: TRIS
  • Created Date: Mar 2 2018 4:05PM