HYDROCARBON METABOLISM BY BREVIBACTERIUM ERYTHROGENES: NORMAL AND BRANCHED ALKANES

Branched and straight chain hydrocarbons are metabolized by Brevibacterium erythrogenes by means of two distinct pathways. Normal alkanes (e.g. n-pentadecane) are degraded, after terminal oxidation, by the beta-oxidation system operational in fatty acid catabolism. Branched alkanes like pristane (2.6.10,14-tetramethylpentadecane) and 2-methylundecane are degraded as dicarboxylic acids, which also undergo beta-oxidation. Pristane-derived intermediates are observed to accumulate, with time, as a series of dicarboxylic acid pathway is not observed in the presence of normal alkanes. Release of (14)CO2 from l-(14) c-pristane is delayed, or entirely inhibited, in the presence of n-hexadecane, while CO2 release from n-hexadecane remains unaffected. These results suggest an inducible dicarboxylic acid pathway for degradation of branched chain alkanes.

  • Corporate Authors:

    Rutgers University, New Brunswick

    Department of Biochemistry and Microbiology
    New Brunswick, NJ  USA  08903
  • Authors:
    • Pirnik, M P
    • Atlas, R M
    • Bartha, R
  • Publication Date: 1974-2-7

Media Info

  • Features: References;
  • Pagination: 35 p.
  • Serial:
    • Issue Number: 4

Subject/Index Terms

Filing Info

  • Accession Number: 00051983
  • Record Type: Publication
  • Source Agency: Rutgers University, New Brunswick
  • Report/Paper Numbers: Tech Rpt
  • Contract Numbers: N00014-67A-0115-0005
  • Files: TRIS
  • Created Date: Apr 9 1974 12:00AM