Interaction of genetic susceptibility and traffic-related air pollution in cardiovascular disease

This thesis aimed at investigating gene-environment interaction in cardiovascular disease. A study population of 618 coronary heart disease cases (of which 192 first-time acute myocardial infarction patients) and 3614 randomly selected population controls was genotyped for genetic variants in genes coding for nitric oxide synthase and glutathione s-transferase. Exposure to traffic-related air pollution was assessed using modeled mean annual concentrations of nitric dioxide as a marker for long-term exposure.

Language

  • English

Media Info

  • Pagination: 68p

Subject/Index Terms

Filing Info

  • Accession Number: 01575448
  • Record Type: Publication
  • Source Agency: Swedish National Road and Transport Research Institute (VTI)
  • ISBN: 9789162892807
  • Files: ITRD, VTI
  • Created Date: Sep 1 2015 11:23AM