Usefulness of Indirect Alcohol Biomarkers for Predicting Recidivism of Drunk-driving among Previously Convicted Drunk-driving Offenders: Results from the Recidivism Of Alcohol-impaired Driving (ROAD) Study

The Recidivism Of Alcohol-impaired Driving (ROAD) study investigated the usefulness of indirect alcohol biomarkers for predicting drunk-driving recidivism in previously convicted drunk-driving offenders. This paper discusses how drivers under the influence (DUI) that are suspected of chronic alcohol abuse are referred for medical and psychological examination in several European countries. The ROAD study is a prospective study that was performed on 517 randomly selected drivers in Belgium between the years 2009 and 2013. These driver were convicted for drunk-driving for which their license was confiscated and the initial post-arrest blood samples were collected and analyzed for percentage carbohydrate-deficient transferrin (%CDT), transaminsase activities [alanine amino transferase (ALT), aspartate amino transferase (AST)], gamma-glutamyltransferase (yGT) and red cell mean corpuscular volume (MCV). Each driver was observed for three (3) years and the percentage of CDT is the major predictor of recidivism of drunk-driving. The association with yGT, ALT and the sex of the driver could have additional value for identifying drunk-drivers at intermediate risk of recidivism. Non-specific indirect alcohol markers, such as ALT, yGT, AST and red cell MCV have minimal added value to %CDT for distinguishing drunk drivers with a low or high risk of recidivism.


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  • Accession Number: 01529529
  • Record Type: Publication
  • Files: TRIS
  • Created Date: Jun 13 2014 2:50PM