On-site testing of cannabis: a controlled study after smoking cannabis

Collection and analysis of drugs in oral fluid using conventional on-site test devices is time consuming, often taking more than 10 minutes. The BIOSENS system, utilizes an alternative approach which implies collection of mucus from the mucosal surface from the tongue with a special designed Oral Mucus Collector (OMC), subsequently analyzed in a BIOSENS system. The collection procedure takes a few seconds and the analysis procedure approximately 60 seconds. The aim of this study is to determine the window of detection and cut off values for THC (delta-9-tetrahydrocannabinol) using the BIOSENS system after smoking one single cannabis cigarette. Eight subjects smoked one cannabis cigarette (THC content 0.3mg/kg body weight). Conventional oral fluid samples and oral mucus samples were collected prior smoking and 1, 2, 3, 4, 5, 6h after smoking. The window of detection using the BIOSENS system was found to be 4 hours for four of the eight subjects, 3h for one subject, 2h for one subject, 1h for one subject and less than 1h for one subject. The window of detection after smoking a single cannabis cigarette was 3-4 hours and the very short sample collection/analysis time opens up possibilities to detect DUI (Driving Under Influence) in practical way. The window of detection is similar to the acute impairment window reported elsewhere. Apart from cannabis, we have observed that other drugs are accumulated in the mucosal surface of the tongue as well. The overall results showed that the BIOSENS system is applicable as an efficient screening method for detecting recent drug use.

• Record URL:
  http://www.icadtsinternational.com/files/documents/2013_078.pdf
• 
• Authors:
  • Mansson, P
  • Nygren, M
  • Lundberg, C
  • Ramaekers, J
• Conference:
  • International Conference on Alcohol, Drugs and Traffic Safety (T2013), 20th, 2013, Brisbane, Queensland, Australia
• Publication Date: 2013-8

Language

• English

Media Info

• Pagination: 486-90
• Monograph Title: 20th International Conference on Alcohol, Drugs and Traffic Safety Conference Proceedings, 25-28 August 2013, Brisbane Convention and Exhibition Centre, Brisbane, Australia

Subject/Index Terms

• TRT Terms: Accuracy; Drivers; Drugged drivers; Drugs; Marijuana; Measuring instruments; Medical examinations and tests; Saliva; Samples; Test procedures
• Uncontrolled Terms: Safe systems (road users)
• Geographic Terms: Netherlands
• ATRI Terms: Accuracy; Drug driving; Marijuana; Measuring equipment; Saliva test; Sample
• Subject Areas: Safety and Human Factors; I83: Accidents and the Human Factor;

Filing Info

• Accession Number: 01500766
• Record Type: Publication
• Source Agency: ARRB
• Files: ITRD, ATRI
• Created Date: Dec 5 2013 8:47AM