HERBICIDE EXPOSURE, MORTALITY AND TUMOR INCIDENCE. AN EPIDEMIOLOGICAL INVESTIGATION ON SWEDISH RAILWAY WORKERS

The investigation shows a slightly dose-dependent and significantly increased tumor incidence and mortality among workers exposed to amitrol (3-animo-1,2,4-triazole), whereas those exposed to phenoxy acids (2,4- dichlorophenoxyacetic acid = 2,4-D and 2,4,5- trichlorophenoxyacetic acid = 2,4,5-T) have about normal tumor incidence and mortality. Based on animal experiments, there is some evidence that amitrol may cause malignant tumors in different tissues, although tumors in the thyroid gland and the liver have been observed and discussed most frequently. Although the investigations may be criticized, the result, being in agreement with animal data, suggests precautions in using amitrol.

• Supplemental Notes:
  • This paper was also published by Lakartidningen, Stockholm, Sweden, pp 2466-70, 1974.
• Corporate Authors:

  Occupational Health Foundation of Finland

  Haartmanink 1
  SF-00290 Helsinki 29,   Finland 
• Authors:
  • Axelsson, O
  • Sundell, L
• Publication Date: 1974

Language

• Finnish

Media Info

• Features: Figures;
• Pagination: p. 21-28
• Serial:
  • Work, Environment, Health
  • Publisher: Occupational Health Foundation of Finland

Subject/Index Terms

• TRT Terms: Herbicides; Human factors; Physiological aspects; Safety; Vegetation control
• Old TRIS Terms: Physiological factors
• Subject Areas: Railroads; Safety and Human Factors;

Filing Info

• Accession Number: 00095393
• Record Type: Publication
• Source Agency: International Railway Documentation, Selection of
• Files: TRIS
• Created Date: Jul 15 1976 12:00AM