INTERACTION BETWEEN MARIHUANA AND ETHANOL: EFFECTS ON PSYCHOMOTOR PERFORMANCE

This is a report of the results of a placebo-controlled study in which the effects of the interaction between ethanol and marihuana on drug plasma concentrations, subjective ratings of intoxication, heart rate acceleration, and psychomoter performance were investigated. The variables measured in the study were subjective rating of ethanol and marihuana intoxication; heart rate; accuracy and latency of response in the simulator evaluation of drug impairment task; blood ethanol concentration gas chromatography; and plasma concentration of the THC (delta-9-tetrahydrocannabinol) by radioimmunoassay. The results indicate that the decrements due to ethanol in performance of skills necessary to drive an automobile were significantly enhanced by marihuana in an additive and perhaps synergistic manner. The administration of ethanol prior to marihuana smoking did not produce significant effects on the subjective rating of 'high,' heart rate acceleration, or THC plasma concentration.

• Availability:
  • Find a library where document is available. Order URL: http://worldcat.org/issn/0002502X
• Corporate Authors:

  Center for Study & Control of Alcohol & Other Add

  Vinogradaska 29
  41000 Zagreb,   Croatia 
• Authors:
  • Perez-Reyes, M
  • Hicks, R E
  • Bumberry, J
  • Jeffcoat, A R
  • Cooke, C E
• Publication Date: 1988

Media Info

• Pagination: p. 268-276
• Serial:
  • Alcoholism
  • Volume: 12
  • Issue Number: 2
  • Publisher: Center for Study & Control of Alcohol & Other Add
  • ISSN: 0002-502X

Subject/Index Terms

• TRT Terms: Alcoholic beverages; Blood alcohol levels; Driver performance; Drivers; Drugs; Ethanol; Impaired drivers; Intoxication; Marijuana; Motor skills; Personnel performance
• Uncontrolled Terms: Psychomotor performance
• Old TRIS Terms: Driver impairment
• Subject Areas: Highways; Safety and Human Factors; I83: Accidents and the Human Factor;

Filing Info

• Accession Number: 00489409
• Record Type: Publication
• Files: TRIS
• Created Date: Nov 30 1989 12:00AM