DRUGS AND DRIVING: A SYSTEMATIC ANALYTICAL APPROACH

To collect useful epidemiological data about drug involvement in highway safety, it is essential that sensitive and specific analytical procedures be used to establish the presence of and to determine the concentrations of drugs and metabolites in samples collected from drivers. This paper describes a comprehensive and systematic screening procedure requiring 6 mL of blood, which has been used for the analysis of samples collecting from injured and fatally injured drivers. The procedure uses radioimmunoassay, gas chromatography with selective detectors, and high performance liquid chromatography. Drugs and metabolites presumptively identified are then confirmed primarily using gas chromatography chemical ionization mass spectrometry.

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  • Corporate Authors:

    American Society for Testing and Materials (ASTM)

    100 Barr Harbor Drive, P.O. Box C700
    West Conshohocken, PA  United States  19428-2957
  • Authors:
    • Crouch, D J
    • Peat, M A
    • Chinn, D M
    • Finkle, B S
  • Publication Date: 1983-10

Media Info

Subject/Index Terms

Filing Info

  • Accession Number: 00396508
  • Record Type: Publication
  • Source Agency: National Highway Traffic Safety Administration
  • Report/Paper Numbers: HS-037 572
  • Files: HSL, TRIS, USDOT
  • Created Date: Aug 31 1985 12:00AM