DRUGS AND DRIVING: A SYSTEMATIC ANALYTICAL APPROACH
To collect useful epidemiological data about drug involvement in highway safety, it is essential that sensitive and specific analytical procedures be used to establish the presence of and to determine the concentrations of drugs and metabolites in samples collected from drivers. This paper describes a comprehensive and systematic screening procedure requiring 6 mL of blood, which has been used for the analysis of samples collecting from injured and fatally injured drivers. The procedure uses radioimmunoassay, gas chromatography with selective detectors, and high performance liquid chromatography. Drugs and metabolites presumptively identified are then confirmed primarily using gas chromatography chemical ionization mass spectrometry.
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Availability:
- Find a library where document is available. Order URL: http://worldcat.org/issn/00221198
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Corporate Authors:
American Society for Testing and Materials (ASTM)
100 Barr Harbor Drive, P.O. Box C700
West Conshohocken, PA United States 19428-2957 -
Authors:
- Crouch, D J
- Peat, M A
- Chinn, D M
- Finkle, B S
- Publication Date: 1983-10
Media Info
- Features: Figures; References; Tables;
- Pagination: p. 945-956
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Serial:
- Journal of Forensic Sciences
- Volume: 28
- Issue Number: 4
- Publisher: Blackwell Publishing
- ISSN: 0022-1198
- EISSN: 1556-4029
- Serial URL: http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1556-4029
Subject/Index Terms
- TRT Terms: Driver performance; Drivers; Drugs; Epidemiology; Gas chromatography; Highway safety; Mass spectrometry; Personnel performance
- Old TRIS Terms: Radioimmunological analysis
- Subject Areas: Highways; Safety and Human Factors; I83: Accidents and the Human Factor;
Filing Info
- Accession Number: 00396508
- Record Type: Publication
- Source Agency: National Highway Traffic Safety Administration
- Report/Paper Numbers: HS-037 572
- Files: HSL, TRIS, USDOT
- Created Date: Aug 31 1985 12:00AM