CHLORMEZANONE: ITS EFFECTS ON SUBJECTIVE ASPECTS OF SLEEP AND ON SKILLED PERFORMANCE RELATED TO CAR DRIVING

A double-blind, crossover study compared chlormezanone 200 mg tds, chlormezanone 400 mg nocte and placebo in twelve female volunteers. There was no obvious evidence of chlormezanone causing an impairment in early morning psychomotor performance, car driving ability of subjective ratings of early morning behaviour. Subjectively reported mood changes were consistent with those expected of a tranquillising drug and the sleep-inducing and improving properties of chlormezanone were confirmed. This volunteer study suggests that chlormezanone may well be a nocturnal sedative which does not have a morning hangover effect. (Author/TRRL)

• Availability:
  • Find a library where document is available. Order URL: http://worldcat.org/issn/03786501
• Corporate Authors:

  JR Prous, SA International Publishers

  Provenza 385-387
  Barcelona,   Spain 
• Authors:
  • HINDMARCH, I
  • GUDGEON, A C
• Publication Date: 1983

Media Info

• Pagination: p. 59-65
• Serial:
  • Methods & Finding in Exper & Clinical Pharmacolgy
  • Volume: 5
  • Issue Number: 1
  • Publisher: JR Prous, SA International Publishers
  • ISSN: 0378-6501

Subject/Index Terms

• TRT Terms: Alcohol effects; Days; Driver performance; Drivers; Driving; Drugs; Females; Hangover; Impaired drivers; Medical examinations and tests; Night; Personnel performance; Physiological fatigue; Placebos; Sleep; Tests
• Old TRIS Terms: Chlormezanone; Driver impairment
• ITRD Terms: 9007: Day (24 hour period); 1855: Driving (veh); 2242: Drugs; 2222: Fatigue (human); 2157: Medical examination; 9052: Night; 6255: Test; 1788: Woman
• Subject Areas: Highways; Safety and Human Factors; I83: Accidents and the Human Factor;

Filing Info

• Accession Number: 00395577
• Record Type: Publication
• Source Agency: Transport Research Laboratory
• Files: ITRD, TRIS
• Created Date: Jan 31 1986 12:00AM