EFFECTS OF ETHANOL: I. ACUTE METABOLIC TOLERANCE AND ETHNIC DIFFERENCES

This study found an increase in alcohol clearance rate within a few hours for most subjects after a second dose of alcohol, a phenomenon termed acute metabolic tolerance to ethanol (AMTE), and reports on some ethnic differences in aspects of ethanol metabolism. The present data question the accuracy of standard methods of estimating the volume of distribution of alcohol and lead to the speculation that the alcohol clearance capacity of the liver is not perfectly correlated with body size, or lean body mass in human populations.

• Corporate Authors:

  University of Colorado, Boulder

  Public Information Office, 382 Willard Administration Center, Box B-9
  Boulder, CO  United States  80309
• Authors:
  • Wilson, J R
  • Erwin, V G
  • McClearn, G E
• Publication Date: 1983

Media Info

• Features: Figures; References; Tables;
• Pagination: 22 p.

Subject/Index Terms

• TRT Terms: Alcoholic beverages; Ethanol; Human factors; Metabolism; Race
• Subject Areas: Safety and Human Factors;

Filing Info

• Accession Number: 00391120
• Record Type: Publication
• Source Agency: National Highway Traffic Safety Administration
• Report/Paper Numbers: HS-037 016
• Files: HSL, USDOT
• Created Date: Nov 30 1984 12:00AM