EFFECTS OF CHRONICALLY ADMINISTERED BUSPIRONE AND DIAZEPAM ON DRIVING-RELATED SKILLS PERFORMANCE

The effects on driving skills of buspirone and diazepam, singly and in combination with alcohol, were examined. Three groups of 16 subjects each (8 men and 8 women) received either 20 mg of buspirone, 15 mg of diazepam, or placebo daily for 9 days. On day 9, they also received alcohol (men, 0.85 g/kg; women, 0.72 g/kg). On days 1, 8, and 9, subjects were tested on a driving simulator and given four sessions of divided attention tasks examining tracking and visual search performance. Extensive evidence of performance impairment associated with diazepam contrasted with improved performance under chronic buspirone treatment. Alcohol effects were additive.

• Availability:
  • Find a library where document is available. Order URL: http://worldcat.org/issn/01606689
• Corporate Authors:

  Physicians Postgraduate Press, Incorporated

  P.O. Box 240008
  Memphis, TN  United States  38124
• Authors:
  • Moskowitz, H
  • Smiley, A
• Publication Date: 1982-12

Media Info

• Features: Figures; References; Tables;
• Pagination: p. 45-55
• Serial:
  • Journal of Clinical Psychiatry
  • Volume: 43
  • Issue Number: 12
  • Publisher: Physicians Postgraduate Press, Incorporated
  • ISSN: 0160-6689
  • Serial URL: http://www.psychiatrist.com/default2.asp

Subject/Index Terms

• TRT Terms: Driver performance; Drivers; Driving; Drugs; Impaired drivers; Motor skills; Personnel performance; Tracking systems
• Uncontrolled Terms: Tracking; Visual search
• Old TRIS Terms: Driver impairment
• Subject Areas: Highways; Safety and Human Factors; I83: Accidents and the Human Factor;

Filing Info

• Accession Number: 00386508
• Record Type: Publication
• Source Agency: National Highway Traffic Safety Administration
• Report/Paper Numbers: HS-036 138
• Files: HSL, TRIS, USDOT
• Created Date: Jun 28 1984 12:00AM