TOLERANCE AND CROSS-TOLERANCE TO MORPHINE AND ETHANOL IN MICE SELECTIVELY BRED FOR DIFFERENTIAL SENSITIVITY TO ETHANOL

Ethanol-sensitive long-sleep mice showed greater sensitivity to ethanol-induced hypothermia whereas the less sensitive short-sleep mice showed greater sensitivity to morphine-induced hypothermia. The short-sleep mice, but not the long-sleep mice, displayed a degree of cross-tolerance to the hypothermic effects of ethanol following repeated exposure to morphine.

• Availability:
  • Find a library where document is available. Order URL: http://worldcat.org/issn/0096882X
• Corporate Authors:

  Rutgers University, New Brunswick

  Center of Alcohol Studies
  New Brunswick, NJ  United States  08903
• Authors:
  • Brick, J
  • Horowitz, G P
• Publication Date: 1983-8

Media Info

• Features: Figures; References; Tables;
• Pagination: p. 770-779
• Serial:
  • Journal of Studies on Alcohol
  • Volume: 44
  • Issue Number: 5
  • Publisher: Rutgers University, New Brunswick
  • ISSN: 0096-882X

Subject/Index Terms

• TRT Terms: Animals; Engineering tolerance; Ethanol; Experiments; Hypothermia; Opioids
• Uncontrolled Terms: Morphine
• Old TRIS Terms: Tolerances
• Subject Areas: Safety and Human Factors;

Filing Info

• Accession Number: 00386034
• Record Type: Publication
• Source Agency: National Highway Traffic Safety Administration
• Report/Paper Numbers: HS-036 035
• Files: HSL, USDOT
• Created Date: Jun 28 1984 12:00AM