Short-term exposure to traffic-related air pollution and STEMI events: Insights into STEMI onset and related cardiac impairment
Aims: Evidence on the impacts of traffic-related air pollution (TRAP) on ST-segment elevation myocardial infarction (STEMI) events is limited. The authors aimed to assess the acute effects of TRAP exposure on the clinical onset of STEMI and related cardiac impairments. Methods and results: The authors recruited patients who were admitted for STEMI and underwent primary percutaneous coronary intervention at Peking University Third Hospital between 2014 and 2020. Indicators relevant to cardiac impairments were measured. Concomitantly, hourly concentrations of traffic pollutants were monitored throughout the study period, including fine particulate matter, black carbon (BC), particles in size ranges of 5–560 nm, oxides of nitrogen (NOₓ), nitrogen dioxide, and carbon monoxide. The mean (SD) age of participants was 62.4 (12.5) years. Daily average (range) concentrations of ambient BC and NOₓ were 3.9 (0.1–25.0) μg/m³ and 90.8 (16.6–371.7) μg/m³. Significant increases in STEMI risks of 5.9% (95% CI: 0.1, 12.0) to 21.9% (95% CI: 6.0, 40.2) were associated with interquartile range increases in exposure to TRAP within a few hours. These changes were accompanied by significant elevations in cardiac troponin T levels of 6.9% (95% CI: 0.2, 14.1) to 41.7% (95% CI: 21.2, 65.6), as well as reductions in left ventricular ejection fraction of 1.5% (95% CI: 0.1, 2.9) to 3.7% (95% CI: 0.8, 6.4). Furthermore, the associations were attenuated in participants living in areas with higher residential greenness levels. Conclusions: The authors' findings extend current understanding that short-term exposure to higher levels of traffic pollution was associated with increased STEMI risks and exacerbated cardiac impairments, and provide evidence on traffic pollution control priority for protecting vulnerable populations who are at greater risks of cardiovascular events.
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Availability:
- Find a library where document is available. Order URL: http://worldcat.org/issn/00489697
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Supplemental Notes:
- © 2022 Elsevier B.V. All rights reserved. Abstract reprinted with permission of Elsevier.
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Authors:
- Zhu, Yutong
- Fan, Yuanyuan
- Xu, Yuan
- Xu, Hongbing
- Wu, Cencen
- Wang, Tong
- Zhao, Menglin
- Liu, Lingyan
- Cai, Jiageng
- Yuan, Ningman
- Guan, Xinpeng
- He, Xinghou
- Fang, Jiakun
- Zhao, Qian
- Song, Xiaoming
- Zu, Lingyun
- Huang, Wei
- Publication Date: 2022-6-25
Language
- English
Media Info
- Media Type: Web
- Features: Appendices; Figures; References; Tables;
- Pagination: 154210
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Serial:
- Science of the Total Environment
- Volume: 827
- Issue Number: 0
- Publisher: Elsevier
- ISSN: 0048-9697
- Serial URL: http://www.sciencedirect.com/science/journal/00489697
Subject/Index Terms
- TRT Terms: Air pollution; Cardiac disorder; Exhaust gases; Highway traffic; Nitrogen oxides; Particulates
- Geographic Terms: Beijing (China)
- Subject Areas: Environment; Highways; Safety and Human Factors;
Filing Info
- Accession Number: 01841326
- Record Type: Publication
- Files: TRIS
- Created Date: Apr 1 2022 8:58AM