Use of potentially driver-impairing drugs among older drivers
Road safety is a major issue among seniors. Potentially Driver-Impairing (PDI) drugs are known to increase the risk of car accident. The aim of this cross-sectional study was to describe PDI-drug consumption among older drivers and determine associated factors. The S.AGES cohort is a French non-interventional real-life prospective study of 3700 community-dwelling participants aged >=65 years old, suffering from type 2 diabetes (T2DM), chronic pain or atrial fibrillation (AF). Baseline data of drivers with known treatment (n = 1783) were used for the analyses. PDI drugs were defined according to the French classification. One thousand seven hundred eighty-three drivers were included (66% males; mean age 76 (Standard deviation = 5.78) years old). 21% (n = 373) took PDI drugs, 64% of which took only one (n = 239). The most frequent PDI drugs were: Zolpidem (11%; n = 60); Zopiclone (8%; n = 45); Bromazepam (8%; n = 44); Tramadol (7%; n = 39); Pregabalin (6%; n = 31). Drivers taking PDI drugs had more often chronic pain (OR [95% CI] = 2.30 [1.54-3.46]), history of depressive disorder (4.28 [3.00-6.14]) and polypharmacy (taking at least 5 different medications; 4.32 [2.97-6.41]), and less often T2DM (0.54 [0.37-0.79]), and AF (0.48 [0.32-0.71]). Conversely, they had a lower Activities of Daily Living score (0.34 [0.17-0.68]). The rate of aged drivers in the S.AGES cohort taking PDI drugs is concerning and highlights the need to carefully assess and reassess PDI-drug prescriptions in this population, particularly hypnotics, anxiolytics and opioids. ClinicalTrials.gov NCT01065909 (First posted: February 9th, 2010).
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Availability:
- Find a library where document is available. Order URL: http://worldcat.org/issn/14712318
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Supplemental Notes:
- Copyright © 2021 Sarah Zitoun, et al.
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Authors:
- Zitoun, Sarah
- Baudouin, Edouard
- Corruble, Emmanuelle
- Vidal, Jean-Sébastien
- Becquemont, Laurent
- Duron, Emmanuelle
- Publication Date: 2022
Language
- English
Media Info
- Media Type: Digital/other
- Pagination: 4
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Serial:
- BMC Geriatrics
- Volume: 22
- Issue Number: 1
- Publisher: BioMed Central
- ISSN: 1471-2318
- Serial URL: http://www.biomedcentral.com/bmcgeriatr/
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Publication flags:
Open Access (libre)
Subject/Index Terms
- TRT Terms: Aged drivers; Behavior; Human factors in crashes; Impaired drivers; Medication
- Subject Areas: Highways; Safety and Human Factors;
Filing Info
- Accession Number: 01848539
- Record Type: Publication
- Files: TRIS
- Created Date: Jun 13 2022 1:14PM