ALCOHOL AND AMITRIPTYLINE EFFECTS ON SKILLS RELATED TO DRIVING BEHAVIOR

DRUGS WHICH ACT ON THE CENTRAL NERVOUS SYSTEM ARE BEING MORE WIDELY PRESCRIBED. SINCE ANIMAL STUDIES INDICATE THAT ANTIDEPRESSANTS MAY ADD TO THE EFFECTS OF ALCOHOL, THE EFFECTS OF AMITRIPTYLINE (A COMMONLY PRESCRIBED ANTI- DEPRESSANT) AND ALCOHOL ON SOME SKILLS RELATED TO DRIVING BEHAVIOR WERE TESTED IN HUMANS. THREE MOTOR-SKILL TESTS RELATED TO DRIVING ABILITY WERE GIVEN TO 21 HEALTHY YOUNG VOLUNTEERS AFTER ADMINISTRATION OF VARIOUS COMBINATIONS OF AMITRIPTYLINE, PLACEBO, AND ALCOHOL. IT WAS FOUND THAT THE TRICYLIC ANTIDEPRESSANT ADDED TO THE DELETERIOUS EFFECTS OF ALCOHOL. /AUTHOR/

• Availability:
  • Find a library where document is available. Order URL: http://worldcat.org/issn/00368075
• Supplemental Notes:
  • Vol 163, No 3874, PP 1467-1468
• Authors:
  • Landauer, A A
  • Milner, G
  • Patman, J
• Publication Date: 1969-3-28

Media Info

• Serial:
  • Science
  • Publisher: American Association for the Advancement of Science
  • ISSN: 0036-8075
  • Serial URL: http://science.sciencemag.org/

Subject/Index Terms

• TRT Terms: Alcohols; Antidepressants; Behavior; Driver performance; Drivers; Drugs; Personnel performance
• Subject Areas: Highways; Safety and Human Factors;

Filing Info

• Accession Number: 00222995
• Record Type: Publication
• Files: TRIS
• Created Date: Jul 14 1994 12:00AM